+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The effects of ascorbic acid and ketotifen in the prevention of murine amyloidosis



The effects of ascorbic acid and ketotifen in the prevention of murine amyloidosis



Turkish Journal of Pediatrics 28(4): 243-248



Amyloidosis was induced in 45 mice by 14 consecutive daily injections of casein solution. The mice were divided at random into three equal groups. The first group was the control. The second group received ascorbic acid and the third group received ketotifen in the drinking water throughout the study. On the fifteenth day there was no difference between the control and the ketotifen groups with respect to splenic amyloidosis. This observation has not previously been reported in the literature, but the protective value of vitamin C in splenic amyloidosis, shown in this study confirms the findings of previous studies.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 001707453

Download citation: RISBibTeXText

PMID: 3590318


Related references

The failure of ascorbic acid therapy to alter the induction or remission of murine amyloidosis. Clinical and Experimental Immunology 57(3): 657-662, 1984

Drug prevention of allergic bronchial asthma. Comparison of the protective effects of ketotifen and cromoglycic acid. Zfa. Zeitschrift für Allgemeinmedizin 58(26): 1425-1428, 1982

Research on the physiology of ascorbic acid: XXVI. Inhibition of greening by indoleacctic acid and its prevention by ascorbic acid. NUOVO G BOT ITAL 68(1/2): 36-42, 1961frecd ], 1966

The beneficial effects of ascorbic acid on murine burns. Journal of Burn Care and Rehabilitation 6(1): 50-54, 1985

Protective effects of ascorbic acid on murine frostbite. Annals of the New York Academy of Sciences98(498): 517-518, 1987

Ascorbic acid and the formation of N-nitroso compounds: possible role of ascorbic acid in cancer prevention. American Journal of Clinical Nutrition 45(5 Suppl.): 1344-1350, 1987

Effects of L-ascorbic acid on apoptosis of B16 murine melanoma cells. FASEB Journal 15(5): A1204, 2001

The effects of cyclophosphamide alone and in combination with ascorbic acid against murine ascites Dalton's lymphoma. Indian Journal of Pharmacology 38(4): 260-265, 2006

Effects in vitro of tocopherol and ascorbic acid upon murine peritoneal macrophage functions. European Journal of Haematology 57(59 Suppl. ): 48, 1996

Ascorbic acid in the prevention and treatment of toxic effects from chromates. Acta Dermato-Venereologica 50(1): 59-64, 1970

In vivo radio modification and combined effects of ascorbic acid with misonidazole on fsa ii murine tumors. International Journal of Radiation Oncology, Biology, Physics 8(10): 1845-1846, 1982

Effects of lipophilic derivatives of L-ascorbic acid and dehydro-L-ascorbic acid on the peroxidation of linoleic acid in neutral phosphate buffer containing alcohol. Journal of Nutritional Science and Vitaminology 32(4): 389-394, 1986

Effects of dietary ascorbic acid and exercise on tissue ascorbic acid, lactate dehydrogenase and thiobarbituric acid reactive substances in guinea pigs. FASEB Journal 7(3-4): A611, 1993

Effects of l ascorbic acid and dehydro l ascorbic acid on the peroxidation of linoleic acid in neutral phosphate buffer containing alcohol. Agricultural & Biological Chemistry 50(1): 41-48, 1986

Preparation of dehydro-l-(+)-ascorbic acid dimer by oxidation of ascorbic acid with arsenic acid/iodine and formation of complexes between arsenious acid and ascorbic acid. Journal of Inorganic Biochemistry 98(4): 649-656, 2004