+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

A positive association between maternal serum zinc concentration and birth weight



A positive association between maternal serum zinc concentration and birth weight



American Journal of Clinical Nutrition 51(4): 678-684



A study was conducted on a cohort of 476 women (364 black, 112 white), who attended the Jefferson County Health Department clinic for their prenatal care, to ascertain the relationship between maternal serum zinc concentration measured early in pregnancy and birth weight. For all subjects maternal serum zinc was significantly related to birth weight after various independent determinants of birth weight were controlled for. The data in this study indicate a threshold for maternal serum zinc concentration below which the prevalence of low birth weight increases significantly. Pregnant women who had serum zinc concentrations in the lowest quartile had significantly higher prevalence of low birth weight than did those mothers who had serum zinc concentrations in the upper three quartiles during pregnancy. These findings suggest that maternal serum zinc concentration measured early in pregnancy could be used to identify those women at higher risk of giving birth to a low-birth-weight infant.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 001740729

Download citation: RISBibTeXText

PMID: 2321574

DOI: 10.1093/ajcn/51.4.678


Related references

Relationship between Low Birth Weight Neonate and Maternal Serum Zinc Concentration. Iranian Red Crescent Medical Journal 14(4): 240-244, 2012

Relationship between birth weight, placental weight and HPL concentration in maternal serum. Acta Paediatrica Academiae Scientiarum Hungaricae 14(3): 221-224, 1973

The relationship between zinc concentration of maternal, umbilical cord, and placenta and birth weight. Korean Journal of Community Nutrition 8(6): 814-821, 2003

High oestradiol concentration after ovarian stimulation is associated with lower maternal serum beta-HCG concentration and neonatal birth weight. Reproductive Biomedicine Online 35(2): 189-196, 2017

Maternal serum zinc level and its relation with neonatal birth weight. Mymensingh Medical Journal 21(4): 588-593, 2012

Association of maternal serum concentration of hydroxylated polychlorinated biphenyls with maternal and neonatal thyroid hormones: The Hokkaido birth cohort study. Environmental Research 167: 583-590, 2018

Association between maternal and umbilical cord serum cobalt concentration during pregnancy and the risk of preterm birth: The Ma'anshan birth cohort (MABC) study. Chemosphere 218: 487-492, 2019

The association of maternal and offspring birth weights under conditions affecting maternal birth weight The Dutch Famine Birth Cohort Study. American Journal of Epidemiology 143(11 Suppl. ): S54, 1996

Maternal hemoglobin concentration and its association with birth weight in newborns of mothers with preeclampsia. Journal of Maternal-Fetal and Neonatal Medicine 22(9): 740-744, 2009

Positive correlation between maternal serum coenzyme Q10 levels and infant birth weight. Biofactors 36(4): 312-318, 2010

Maternal Serum Zinc Concentration during Pregnancy Is Inversely Associated with Risk of Preterm Birth in a Chinese Population. Journal of Nutrition 146(3): 509-515, 2016

The association between Porphyromonas gingivalis-specific maternal serum IgG and low birth weight. Journal of Periodontology 72(11): 1491-1497, 2001

Very low second-trimester maternal serum alpha-fetoprotein: Association with high birth weight. Obstetrics & Gynecology 99(4): 531-536, 2002

Association between maternal serum concentration of the DDT metabolite DDE and preterm and small-for-gestational-age babies at birth. Lancet 358(9276): 110-114, 2001

Retinol concentration in maternal and cord serum: its relation to birth weight in healthy mother-infant pairs. Early Human Development 71(1): 19-28, 2003