Acanthamoeba keratitis. An important consideration when evaluating ocular complaints in contact lens wearers
White, G.L.; Lundergan, M.K.; Thiese, S.M.; Murdock, R.T.
Journal of Family Practice 27(1): 104 106-7
ISSN/ISBN: 0094-3509 PMID: 3392503 Accession: 001745374
A. castellanii keratitis is reported in an 18-year-old male soft contact lens wearer in Utah, USA. The patient was treated with neomycin-polymyxin B-dexamethasone (4 times/day), topical propamidine (4 times/day), oral ketoconazole (200 mg 4 times/day), 1% prednisolone acetate (4 times/day), homatropine (4 times/day), and 5% sodium chloride ointment (2 times/day). Four months later the patient presented with severe pain and photophobia in the left eye. Ocular examination revealed a ring of corneal infiltrate and 2 areas of epithelial defect with 50% thinning. Cultures were negative for A. castellanii at 72 h and penetrating keratoplasty was performed because of impending corneal perforations.