+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Age-related changes in lipid metabolism in rats: the consequence of moderate food restriction

, : Age-related changes in lipid metabolism in rats: the consequence of moderate food restriction. Biochimica et Biophysica Acta 963(2): 237-242

Male Sprague-Dawley rats, 3 weeks of age, received one of the four following dietary manipulations until 9 months of age: group AD, fed ad libitum; group R, restricted to 75% of food intake of group AD; group RAD, restricted until 5 months of age and then fed ad libitum; group ADR, fed ad libitum until 5 months of age and the restricted. The concentration of serum total and HDL cholesterol tended to be higher in group AD and than in all groups that had experienced food restriction. Liver cholesterol was higher in groups AD and RAD than in groups R and ADR. Activity of hepatic microsomal hydroxymethylglutaryl-CoA reductase was comparable, whereas sterol synthesis from mevalonate was significantly higher in groups R and ADR than in groups AD and RAD. Cholesterol 7 alpha-hydroxylase activity also tended to be higher in groups R and ADR. It seems likely that hepatic cholesterol homeostasis functions effectively even when moderate food restriction was started after the growing period. In addition, food restriction reduced the ratio of arachidonate to linoleate, suggesting inhibition of the desaturation system.

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 001748293

PMID: 3196729

DOI: 10.1016/0005-2760(88)90286-x

Download PDF Full Text: Age-related changes in lipid metabolism in rats: the consequence of moderate food restriction

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Wrensch, M.; Swan, S.H.; Lipscomb, J.; Epstein, D.M.; Neutra, R.R.; Fenster, L., 1992: Spontaneous abortions and birth defects related to tap and bottled water use, San Jose, California, 1980-1985. We recently studied pregnancies occurring during 1980-1985 in four study areas in Santa Clara County, California. Two of the areas were exposed to solvent-contaminated drinking water during 1980 and 1981, and two were unexposed. There was an overa...

Ute Christina Herzfeld, 1989: Variography of submarine morphology; problems of deregularization, and cartographical implications. During the German Antarctic Expedition VI (leg 3, December 1987 to March 1988), bathymetric surveys were made in the Weddell Sea by the SEABEAM sonar system. For the first time geostatistical methods were applied in the SEABEAM-postprocessing. The...

Anonymous, 2012: Sequestration of PDC-19 protein improves freezability of crossbred bull spermatozoa. A study was carried out to assess the effect of sequestration of PDC-19 protein, a majority constituent of Heparin binding proteins (HBP) of seminal plasma, on freezability andin vitrofertilizing ability of crossbred bull spermatozoa after cryopre...

Martz, C.H., 1992: Targeting young and old for skin cancer awareness. Oncology Nursing Forum 19(1): 92-92

Assche, C.V.n; Wambeke, E.V.n; Vanachter, A., 1975: Some specific problems related to the use of systemic fungicides in lettuce and tomato. Parasitica 1 (4) 123-133

Goldstein, G.B., 1983: Comment on Medicare: a DRS viewpoint. Australian Health Review 7(1): 34-36

Jainandunsing, J.S.; Al-Ansari, S.; Woltersom, B.D.; Scheeren, T.W.L.; Natour, E., 2015: Novel hemostatic patch achieves sutureless epicardial wound closure during complex cardiac surgery, a case report. Treatment of damaged cardiac tissue in patients with high bleeding tendency can be very challenging, damaged myocardial tissue has a high rupture risk when being sutured subsequently on-going bleeding is a major risk factor for poor clinical outco...

Balaskó, M.; Petervári, E.; Szelenyi, Z.; Szekely, M., 2001: The effects of centrally adminstered neuropeptide Y on thermoregulation. Neurobiology 9(1): 31-32

Miadonna, A.; Milazzo, N.; Lorini, M.; Marchesi, E.; Tedeschi, A., 1994: Inhibitory effects of the H-1 antagonist loratadine on histamine release from human basophils. Loratadine is a powerful H-1 antagonist commonly employed in the treatment of allergic disorders. The present study was performed to investigate whether loratadine, in addition to anti-H-1 activity, is able to modulate histamine release from human...

Anonymous, 1965: Standards recommended for public health schools of Latin America. Salud Publica de Mexico 7(2): 307-312