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Age-related changes in the fibre composition of equine peripheral nerve


, : Age-related changes in the fibre composition of equine peripheral nerve. Journal of the Neurological Sciences 90(1): 53-66

Transverse sections of the lateral palmar nerve from a group of horses free from neuromuscular disease were assessed quantitatively, with emphasis on differences in the fibre population related to age. Morphometric analysis of the population of myelinated and unmyelinated fibres was performed. Changes were identified, there being a loss of larger myelinated fibres in older horses. The relationship of myelin thickness to axon diameter and the umyelinated fibre population did not alter with age. The lateral palmar nerve is suitable for biopsy and electrophysiological study in the horse, but age related changes must be appreciated in the interpretation of results.

Accession: 001748303

PMID: 2723674

DOI: 10.1016/0022-510x(89)90045-2

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Related references

Wheeler S.J.; Plummer J.M., 1989: Age related changes in the fiber composition of equine peripheral nerve. Transverse sections of the lateral palmar nerve from a group of horses free from neuromuscular disease were assessed quantitatively, with emphasis on differences in the fibre population related to age. Morphometric analysis of the population of my...

Wheeler, S.J., 1990: Quantitative and qualitative morphology of equine peripheral nerve: teased fibre studies. Single teased fibre studies were made on samples of the lateral palmar nerve from 16 horses of mixed age and size which had no evidence of neuromuscular disease. Significant proportions of abnormal fibres indicative of axonal degeneration/regenera...

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