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Age-related changes in the fibre composition of equine peripheral nerve


Journal of the Neurological Sciences 90(1): 53-66
Age-related changes in the fibre composition of equine peripheral nerve
Transverse sections of the lateral palmar nerve from a group of horses free from neuromuscular disease were assessed quantitatively, with emphasis on differences in the fibre population related to age. Morphometric analysis of the population of myelinated and unmyelinated fibres was performed. Changes were identified, there being a loss of larger myelinated fibres in older horses. The relationship of myelin thickness to axon diameter and the umyelinated fibre population did not alter with age. The lateral palmar nerve is suitable for biopsy and electrophysiological study in the horse, but age related changes must be appreciated in the interpretation of results.

Accession: 001748303

PMID: 2723674

DOI: 10.1016/0022-510x(89)90045-2

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