Section 2
Chapter 1,757

Antifilarial activities of benzazole derivatives. 1. Macrofilaricidal effects against Litomosoides carinii, Dipetalonema viteae, Brugia malayi, and B. pahangi in Mastomys natalensis

Zahner, H.; Striebel, H.P.; Schütze, H.R.; Sänger, I.; Müller, H.A.; Schultheiss, K.

Tropical Medicine and Parasitology Official Organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit 39(1): 14-18


ISSN/ISBN: 0177-2392
PMID: 3387822
Accession: 001756972

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Eighteen 2-tert-butyl-benzazole derivatives were evaluated as macrofilaricidal agents against L. carinii, D. viteae, B. malayi and B. pahangi. In M. natalensis, upon oral treatment once daily for 5 consecutive days the 8 benzoxazole derivatives were invariably less potent than the corresponding benzothiazole derivatives.

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