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Comparative effects of eight azole derivatives on Candida albicans: fungistatic activity and cytological effects studied by scanning electron microscopy


Pathologie Biologie 36(5): 575-580
Comparative effects of eight azole derivatives on Candida albicans: fungistatic activity and cytological effects studied by scanning electron microscopy
The in vitro antifungal activity of 8 imidazole derivatives (clotrimazole, econazole, isoconazole, ketoconazole, miconazole, oxiconazole, terconazole, tioconazole) against 42 C. albicans isolates was compared by agar dilution method using casitone medium. The geometric (G) mean min. inhibitory concn (MIC) values, the MIC 90 and the MIC 50 values and the corresponding standard deviations of each antifungal agent were determined. The G-MIC values were found to be 0.008-0.390 micro g/ml.


Accession: 001780828



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