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Cyclic AMP-dependent protein kinase activity in Trypanosoma cruzi



Cyclic AMP-dependent protein kinase activity in Trypanosoma cruzi



Biochemical Journal 255(1): 319-326



A cyclic AMP-dependent protein kinase activity from epimastigote forms of T. cruzi was characterized. Cytosolic extracts were chromatographed on DEAE-cellulose columns, giving 2 peaks of kinase activity, which were eluted at 0.15 M and 0.32 M NaCl respectively. The 2nd activity peak was stimulated by nanomolar concentrations of cyclic AMP. In addition, a cyclic AMP-binding protein co-eluted with the 2nd kinase activity peak.

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Accession: 001790916

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PMID: 2848508



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