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Effectiveness of spaced doses of diethylcarbamazine citrate for the control of bancroftian filariasis



Effectiveness of spaced doses of diethylcarbamazine citrate for the control of bancroftian filariasis



Tropical Medicine and Parasitology 40(2): 111-113



Forty-seven Wuchereria bancrofti microfilaria carriers in Haiti, were treated once weekly for 12 weeks with 6 mg/kg diethylcarbamazine citrate (DEC-C). Microfilaria densities ranged from 1 to 101 mf/20 mmsuperscript 3 (MfD-50 of 9.75 mf/20 mmsuperscript 3) before treatment. Of 42 persons who completed treatment, 26 were microfilaria negative in 1-ml venous blood samples. Microfilaria densities in the 16 patients that remained positive ranged from 1 to 50 mg/ml (MfD-50 of 2.59 mf/ml).

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Accession: 001816048

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PMID: 2672282


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