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Effects of the number, stage and parental origin of nuclei in reconstructed mouse eggs

Journal of Reproduction and Fertility. Supplement 38: 99-105

Effects of the number, stage and parental origin of nuclei in reconstructed mouse eggs

A review, largely of the authors' own work, in which it is shown that the ability to alter the nuclear constitution of eggs has enabled the functional differences in the 2 parental genomes, the stability of the imprinting modification(s) and the relative inability of egg cytoplasm to reprogramme advanced, active nuclei to be uncovered.

Accession: 001820552

PMID: 2677353

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