EurekaMag.com logo
+ Site Statistics
References:
53,214,146
Abstracts:
29,074,682
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Effects of undernutrition during suckling on phosphoryl serine levels in nuclear and synaptosomal proteins from cerebral cortex of rats


Journal of Nutrition 120(6): 594-597
Effects of undernutrition during suckling on phosphoryl serine levels in nuclear and synaptosomal proteins from cerebral cortex of rats
The effect of undernutrition during suckling of phosphoryl serine levels was investigated in rats. Young rats were undernourished by suckling their lactating mothers fed an 8% (by weight) protein diet. Mothers of normal rats were fed a 25% protein diet. After weaning (21 d), normal and undernourished rats were fed a 25% protein diet until 90-120 d of age. Previously we observed that undernutrition during suckling decreases the levels of phosphoryl serine in nuclear proteins from the whole brain of adult rats. In this paper we report more specifically on the effect of undernutrition during this period on the levels of phosphoryl serine in nuclear and synaptosomal proteins from the cerebral cortex of young and nutritionally rehabilitated adult rats. In young, undernourished rats the levels of phosphoryl serine in nuclear proteins were significantly lower (28%) than those in control animals. This alteration persisted in nutritionally rehabilitated adult rats. Serine and protein levels in cerebral cortex were the same in all groups. No alteration in the levels of phosphoryl serine in the synaptosomal fraction was observed.

(PDF 0-2 workdays service: $29.90)

Accession: 001820770

PMID: 2112593



Related references

Effects of undernutrition during suckling on phosphoryl-serine levels in brain nuclear proteins of adult rats. Journal of Nutrition 116(11): 2303-2310, 1986

Effects of undernutrition during suckling on ATP and ADP hydrolysis by synaptosomes from the cerebral cortex of adult rats. Brazilian Journal of Medical and Biological Research 24(5): 515-526, 1991

Early undernutrition increases glycogen content and reduces the activated forms of GSK3, AMPK, p38 MAPK, and JNK in the cerebral cortex of suckling rats. Journal of Neurochemistry 112(1): 123-133, 2010

Effects of undernutrition and handling during suckling on shuttle avoidance and footshock escape behavior and on plasma glucose levels of young rats. Developmental Psychobiology 23(2): 157-168, 1990

Effects of undernutrition on glutamatergic parameters in the cerebral cortex of young rats. Physiology & Behavior 94(4): 580-585, 2008

In vitro and in vivo effects of HgCl2 on synaptosomal ATP diphosphohydrolase (EC 3.6.1.5) from cerebral cortex of developing rats. Archives Internationales de Physiologie, de Biochimie et de Biophysique 102(5): 251-254, 1994

Successful prediction of immediate effects of undernutrition throughout the brain growth spurt on capillarity and synapse-to-neuron ratio of cerebral cortex in rats. Metabolic Brain Disease 9(1): 81-95, 1994

The effects of electromagnetic pulse on the protein levels of tight junction associated-proteins in the cerebral cortex, hippocampus, heart, lung, and testis of rats. Biomedical and Environmental Sciences 24(4): 438-444, 2012

Effects of subchronic treatment with phenazepam and synthetic antioxidants on the functional state of synaptosomal membranes from the cerebral cortex of rats exposed to long term stress. Byulleten' Eksperimental'noi Biologii i Meditsiny 105(1): 38-40, 1988

Study of synaptosomal and mitochondrial proteins of rat cerebral cortex by electrophoresis in poly acrylamide gel. Biochemistry (Moscow) 37(3 PART 1): 440-445, 1972