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Enzyme-linked immunosorbent assays for Lyme disease: reactivity of subunits of Borrelia burgdorferi


Enzyme-linked immunosorbent assays for Lyme disease: reactivity of subunits of Borrelia burgdorferi



Journal of Infectious Diseases 159(1): 43-49



ISSN/ISBN: 0022-1899

PMID: 2909642

DOI: 10.2307/30136426

"prepared fractions of Borrelia burgdorferi, the etiologic agent of Lyme disease, from cultured spirochetes and used them as antigen in an enzyme-linked immunosorbent assay (ELISA) for IgG antibody. Polystyrene plates coated with an extract containing major proteins with apparent molecular masses of 34, 39, 59, and 68 kilodaltons had comparable sensitivity but greater specificity than plates coated with whole cells.

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Accession: 001825039

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