+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn

+ Translate
+ Recently Requested

Excretion of purine derivatives by ruminants: endogenous excretion, differences between cattle and sheep



Excretion of purine derivatives by ruminants: endogenous excretion, differences between cattle and sheep



British Journal of Nutrition 63(1): 121-129



The endogenous urinary excretion of the purine derivatives allantoin, uric acid and xanthine plus hypoxanthine were measured in twenty-nine lambs, ten cattle (six steers, one cow and three preruminant calves) and four pigs. The sheep and mature cattle were nourished by intragastric infusion and the calves were given a milk-substitute. The pigs were fed on a purine-free diet. The excretion of total purine derivatives was substantially greater by the cattle, being 514 (SE 20.6) micromol/kg live weight (W)0.75 per d compared with 168 (SE 5.0) micromol/kg W0.75 per d by the sheep and 166 (SE 2.6) micromol/kg W0.75 per d by the pigs. Plasma from normally fed sheep, cows and pigs was incubated with either xanthine or uric acid. Sheep and pig plasma had no xanthine oxidase (EC 1.2.3.2) activity whereas plasma from cattle did. Uricase (EC 1.7.3.3) was not present in plasma of cattle and pigs and appeared to be present in trace amounts only in sheep plasma. It is suggested that the species differences in endogenous purine derivative excretion were probably due to the different profiles of xanthine oxidase activity in tissues and particularly in the blood. This is because a high xanthine oxidase activity would reduce the chance to recycle purines, by increasing the probability of degradation to compounds which could not be salvaged.

(PDF emailed within 0-6 h: $19.90)

Accession: 001831134

Download citation: RISBibTeXText

PMID: 2317473

DOI: 10.1079/bjn19900097



Related references

Excretion of purine derivatives by ruminants: effect of exogenous nucleic acid supply on purine derivative excretion by sheep. British Journal of Nutrition 63(1): 131-142, 1990

Excretion of purine derivatives by ruminants effect of microbial nucleic acid infusion on purine derivative excretion by steers. Journal of Agricultural Science 114(3): 243-248, 1990

Causes of differences in urinary excretion of purine derivatives in buffaloes and cattle. Animal science: an international journal of fundamental and applied research 82(3): 355-358, 2006

Excretion of endogenous and exogenous purine derivatives in sheep: effect of increased concentrate intake. British Journal of Nutrition 79(3): 237-240, 1998

Endogenous excretion of purine derivatives, creatinine and nitrogen in crossbred (Bos indicus x Bos taurus) cattle. Animal Nutrition and Feed Technology 7(1): 11-19, 2007

Excretion of purine derivatives by sheep and cattle and its use for the estimation of absorbed microbial protein. Excretion of purine derivatives by sheep and cattle and its use for the estimation of absorbed microbial protein: 239, 1989

Effect of level of feed intake on the excretion of purine derivatives and purine derivatives to creatinine ratio in the urine of sheep. Asian-Australasian Journal of Animal Sciences 5(3): 465-468, 1992

Excretion of purine derivatives in cows: Endogenous contribution and recovery of exogenous purine bases. Livestock Production Science 68(2-3): 243-250, March, 2001

The effect of exogenous purine supply on the endogenous excretion of purine derivatives in the urine of growing lambs. Animal Science Journal 77(6): 582-586, 2006

Estimation of microbial protein in ruminants based on purine derivatives excretion. 2006

Excretion of purine derivatives by ruminants: recycling of allantoin into the rumen via saliva and its fate in the gut. British Journal of Nutrition 63(2): 197-205, 1990

Endogenous excretion of purine derivatives and nitrogen in rams. Indian Journal Of Animal Sciences: 9, 991-996, 2008

Urinary excretion of purine derivatives and tissue xanthine oxidase activity in buffaloes with special reference to differences between buffaloes and Bos taurus cattle. British Journal of Nutrition 75(3): 397-407, 1996

The effect of protein infusion on urinary excretion of purine derivatives in ruminants nourished by intragastric nutrition. Journal of Agricultural Science 109(1): 7-12, 1987