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Exogenous induction of corticosterone surge and its effect on immunoglobulin absorption in the neonatal mouse pup



Exogenous induction of corticosterone surge and its effect on immunoglobulin absorption in the neonatal mouse pup



1987-88 Virginia Tech Livestock Research Report: 1988; 58-61



A study was conducted utilizing 20 litters of white mice (10 young/litter) to estimate the impact of corticosterone on immunoglobulin (Ig) G and IgM absorption in the neonatal mouse. Treatments of corticotropin (ACTH; 10 IU/young) or control (saline) were given intramuscularly on day 10 after birth. Blood was taken at death at 2 h, 2, 4, 6 and 8 days after treatment and pooled within litters for analysis. The ACTH treatment caused a corticosterone peak to occur 2 h after treatment.

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Accession: 001831246

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