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Experimental T-2 toxicosis in swine following inhalation exposure: effects on pulmonary and systemic immunity, and morphologic changes

Experimental T-2 toxicosis in swine following inhalation exposure: effects on pulmonary and systemic immunity, and morphologic changes

Toxicologic Pathology 15(3): 308-319

Thirty-four, 9- to 11-week-old, male castrated, crossbred, specific pathogen-free derived pigs were exposed to a T-2 toxin aerosol at a nebulized dose of 0 or 9 mg/kg in pairs, each pair consisting of 1 control and 1 T-2 treated pig which were exposed on the same day. Twenty to 30% of the toxin (1.8-2.7 mg/kg) was retained by the pigs. Five pairs were killed on each of 1, 3 and 7 d after dosing.

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Accession: 001831612

Download citation: RISBibTeXText

PMID: 3685791

DOI: 10.1177/019262338701500309

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