+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Experimental selenium toxicity in guinea pigs: biochemical studies



Experimental selenium toxicity in guinea pigs: biochemical studies



Annals of Nutrition and Metabolism 33(1): 57-63



Biochemical studies were conducted in experimentally induced selenium toxicity in recently weaned guinea pigs. A significant drop in blood glucose level, in comparison to controls, was observed in animals fed selenium-enriched barley (organic form) as well as those fed ordinary barley mixed with sodium selenite (inorganic form). Estimation of total serum proteins also revealed a significant drop in both these groups. SGOT (EC 2.6.1.1) activity was comparatively lower but no significant alteration was noticed in SGPT (EC 2.6.1.2). The erythrocytic glutathione peroxidase activity was significantly increased in inorganic selenosis followed by that in organic one, in comparison to controls. All these alterations were of mild degree in guinea pigs which were given sodium arsenite (10 ppm) along with sodium selenite (30 ppm) in the feed.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 001831958

Download citation: RISBibTeXText

PMID: 2742331

DOI: 10.1159/000177521


Related references

Experimental selenium toxicity in guinea pigs: biochemical studies. Annals of Nutrition and Metabolism 33(1): 57-63, 1989

Experimental selenium depletion repletion in young men balance studies. Federation Proceedings 39(3): ABSTRACT 369, 1980

Studies on some aspects of histopathology in experimental coccidiosis in chicken. Indian journal of poultry science 20(4): 310-313, 1985

Experimental studies on selective fixation of fibulotalar ligaments without plaster cast. Langenbecks Archiv fuer Chirurgie 364: 546, 1984

Experimental salmonellosis in Japanese quails. Journal of Veterinary and Animal Sciences 27(2): 111-115, 1996

Animal experimental studies of the possible changeability of the allergic disposition; exemplified by epidermal sensitization from dinitrochlorbenzene. Zeitschrift für Haut- und Geschlechtskrankheiten 18(10): 304-310, 1955

Experimental animal studies on penicillin toxicity. I. The effects of penicillin on the pregnant organism with special reference to the guinea pig. Zeitschrift für Hygiene und Infektionskrankheiten; Medizinische Mikrobiologie Immunologie und Virologie 140(3): 248-263, 1954

Studies on the influence of BCG inoculation to experimental tuberculous guinea pigs. Report 3. Studies on the number of tuberculous bacilli in the organs and the reaction of organs in guinea pigs. Nagasaki Med Jour 34(6): 694-700, 1959

Histochemical and biochemical studies of membrane differentiation glucose 6 phosphatase as a marker enzyme. Journal of Cell Biology 43(2 Part 2): 80A, 1969

Toxicity of selected pesticides to lake phytoplankton measured using photosynthetic inhibition compared to maximal uptake rates of phosphate and ammonium. Environmental Toxicology and Chemistry 14(1): 93-98, 1995

Experimental control of floral reversion in isolated shoot apices of the long-day plant Silene coeli-rosa. Physiologia Plantarum 92(2): 329-335, 1994

Biochemical and histological changes during in vitro organogenesis in Jatropha integerrima. Biologia Plantarum 43(2): 167-171, 2000

Studies on the pathogenesis of experimental anti tubular basement membrane nephritis in the guinea pig. American Journal of Pathology 83(3): 531-546, 1976