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Heat inactivation of human immunodeficiency virus type 2 (HIV-2)



Heat inactivation of human immunodeficiency virus type 2 (HIV-2)



Journal of Biological Standardization 17(4): 377-379



HIV-1 has been shown to be particularly heat sensitive. HIV-2 is assumed to be similarly heat sensitive. In order to prove this, the authors heated HIV-1, HIV-2 and Rous sarcoma virus (RSV) for different times in different conditions and measured residual activity of each virus. Titrations were performed on cultures of the same cell type as used for virus propagation. HIV activity was assessed by reverse transcriptase assay, fixed cell immunofluorescence and for HIV-1, giant cell formation.

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Accession: 001850076

Download citation: RISBibTeXText

PMID: 2559084

DOI: 10.1016/s0092-1157(89)80009-5


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