+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Heat shock proteins and immunity

Heat shock proteins and immunity

Research in Immunology 140(7): 653-659

Antibodies to a 56 kDa nuclear protein have been found in the sera of 85% of patients with myositis using an immunoblotting technique. This auto-antibody appears to be relatively disease-specific though more frequently detectable in both adult and childhood onset dermatomyositis. In adult patients with myositis the anti-56 kDa antibody level reflects disease activity. This antibody is thus much more frequently found than previously described disease-specific autoantibodies in patients with myositis such as the Jo-1 antibody, and may represent a useful diagnostic aid in patients with muscle weakness.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 001850130

Download citation: RISBibTeXText

PMID: 2687988

DOI: 10.1016/0167-5699(89)90029-7

Related references

On the model of feedback regulation of heat shock gene expression by heat shock proteins Demonstration of heat shock protein 70-containing complexes of unactivated heat shock transcription factor 1. Protein Engineering 8(Suppl. ): 35, 1995

Heat shock-induced dendritic cell maturation is coupled by transient aggregation of ubiquitinated proteins independently of heat shock factor 1 or inducible heat shock protein 70. Molecular Immunology 41(8): 785-792, 2004

Heat shock proteins in immunity. Handbook of Experimental Pharmacology 2006(172): 279-304, 2006

Distinct heat-shock element arrangements that mediate the heat shock, but not the late-embryogenesis induction of small heat-shock proteins, correlate with promoter activation in root-knot nematode feeding cells. Plant Molecular Biology 66(1-2): 151-164, 2008

Heat-shock proteins: immunity and autoimmunity. Current Opinion in Immunology 4(4): 396-400, 1992

Heat shock proteins and innate immunity. Clinical and Experimental Immunology 127(1): 1-3, 2002

Heat shock proteins: immunity and immunopathology. Immunology Today 11(7): 228-229, 1990

A few considerations on the heat shock proteins in immunity. Romanian Journal of Internal Medicine 43(1-2): 35-47, 2005

Immunity to heat shock proteins and atherosclerosis. van Eden, W , Reprint Author Heat shock proteins and inflammation: 159-173, 2003

Heat shock proteins, immunity and glaucoma. Brain Research Bulletin 62(6): 473-480, 2004

Immunity to heat shock proteins and pregnancy outcome. Infectious Diseases in Obstetrics and Gynecology 7(1-2): 35-38, 1999

The roles of heat shock proteins in tumor immunity. Cancer ChemoTherapy and Biological Response Modifiers 19: 371-383, 2001

Immunity to heat shock proteins and arthritic disorders. Infectious Diseases in Obstetrics and Gynecology 7(1-2): 49-54, 1999

Immunity to heat shock proteins in rheumatoid arthritis. Clinical and Experimental Rheumatology 8(Suppl. 5): 69-74, 1990

Heat shock proteins as antigens in immunity against infection and self. Morimoto, R I, Tissieres, A, Georgopoulos, C Cold Spring Harbor Monograph Series; The biology of heat shock proteins and molecular chaperones 495-531, 1994