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Intramuscular quinine kinetics in Myanmar children with falciparum malaria


, : Intramuscular quinine kinetics in Myanmar children with falciparum malaria. Myanmar Health Sciences Research Journal 2(1): 47-49

Plasma quinine levels were measured in 10 children in Myanmar with acute falciparum malaria during an intramuscular quinine treatment regimen of 20 mg/kg loading dose followed by 10 mg/kg 8-hourly for 3 doses (then oral quinine until day 7). (Unfortunately the only details given concerning severity were that 5 children had parasitaemias over 5%.) The mean time to peak concentration was 3.2 h and the mean peak concentration after the first dose was 12.5 mg/l.

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