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Intramuscular quinine kinetics in Myanmar children with falciparum malaria






Myanmar Health Sciences Research Journal 2(1): 47-49

Intramuscular quinine kinetics in Myanmar children with falciparum malaria

Plasma quinine levels were measured in 10 children in Myanmar with acute falciparum malaria during an intramuscular quinine treatment regimen of 20 mg/kg loading dose followed by 10 mg/kg 8-hourly for 3 doses (then oral quinine until day 7). (Unfortunately the only details given concerning severity were that 5 children had parasitaemias over 5%.) The mean time to peak concentration was 3.2 h and the mean peak concentration after the first dose was 12.5 mg/l.

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Accession: 001869025



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