EurekaMag.com logo
+ Site Statistics
References:
53,214,146
Abstracts:
29,074,682
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Intramuscular quinine kinetics in Myanmar children with falciparum malaria



Intramuscular quinine kinetics in Myanmar children with falciparum malaria



Myanmar Health Sciences Research Journal 2(1): 47-49



Plasma quinine levels were measured in 10 children in Myanmar with acute falciparum malaria during an intramuscular quinine treatment regimen of 20 mg/kg loading dose followed by 10 mg/kg 8-hourly for 3 doses (then oral quinine until day 7). (Unfortunately the only details given concerning severity were that 5 children had parasitaemias over 5%.) The mean time to peak concentration was 3.2 h and the mean peak concentration after the first dose was 12.5 mg/l.

(PDF 0-2 workdays service: $29.90)

Accession: 001869025

Download citation: RISBibTeXText



Related references

The effect of intramuscular loading dose of quinine on Myanmar patients (children and adults) with falciparum malaria. Myanmar Health Sciences Research Journal 6(2): 78-81, 1994

The safety and kinetics of intramuscular quinine in Malawian children with moderately severe falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene 84(4): 482-487, 1990

Comparison of intramuscular sulfadoxine-pyrimethamine and intramuscular quinine for the treatment of falciparum malaria in children. Transactions of the Royal Society of Tropical Medicine and Hygiene 85(3): 341-344, 1991

The pharmacokinetic properties of intramuscular quinine in Gambian children with severe falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene 84(4): 488-491, 1990

Intrarectal quinine versus intravenous or intramuscular quinine for treating Plasmodium falciparum malaria. Cochrane Database of Systematic Reviews (): Cd004009-Cd004009, 2009

Comparison of intramuscular artemether and intravenous quinine in the treatment of Sudanese children with severe falciparum malaria. East African Medical Journal 79(12): 621-625, 2002

Population pharmacokinetic and pharmacodynamic properties of intramuscular quinine in Tanzanian children with severe Falciparum malaria. Antimicrobial Agents and ChemoTherapy 57(2): 775-783, 2013

Comparison of intramuscular artemether and intravenous quinine in the treatment of Sudanese children with severe falciparum malaria. East African Medical Journal 79(12): 621-625, 2003

The effect of halofantrine versus quinine on patients with uncomplicated falciparum malaria in Myanmar. Myanmar Health Sciences Research Journal 5(2): 95-99, 1993

Open comparison of intramuscular chloroquine and quinine in children with severe chloroquine-sensitive falciparum malaria. Lancet 2(8675): 1313-1316, 1989

Intramuscular loading dose of quinine for falciparum malaria: pharmacokinetics and toxicity. British Medical Journal 293(6538): 11-13, 1986

A comparative study on the use of intramuscular chloroquine and quinine (as Quinimax) in the treatment of uncomplicated falciparum malaria in adults. East African Medical Journal 56(4): 158-162, 1979

Randomized comparison of intramuscular artemether and intravenous quinine in adult, Melanesian patients with severe or complicated, Plasmodium falciparum malaria in Papua New Guinea. Annals of Tropical Medicine and Parasitology 92(2): 133-139, 1998