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Is peptide YY trophic to the intestinal epithelium of parenterally fed rats?


Digestion 46 Suppl 2: 177-181
Is peptide YY trophic to the intestinal epithelium of parenterally fed rats?
Rats maintained intravenously were infused with peptide tyrosine tyrosine (PYY) 0, 5, 20 or 80 mu g daily for 3 days. After 3 days the rats were given by injection vincristine 1 mg/kg in order to arrest cells entering metaphase and were killed 2 h later. The gastrointestinal tract was removed, weighed and fixed. Samples of small intestine and colon were stained, microdissected and the mean number of metaphases per crypt was estimated.


Accession: 001871104

PMID: 2124556



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