+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Neurohumoral control of villous motility

Neurohumoral control of villous motility

American Journal of Physiology 255(2 Pt 1): G162-G167

A quantitative videomicroscopic method was used to examine neurohumoral control of villous motility. Intraduodenal instillation of saline, 0.4% hydrochloric acid, or acidified predigested food not cause a significant change in villous contraction frequency in an isolated segment of jejunum. Villous motility in the jejunum of fed dogs, from which the chyme had been removed, was not greater than that in fasted dogs (2.9 .+-. 0.3 vs 3.4 .+-. 0.5 contractions/min). Furthermore, acid extracts of the duodenal mucosa did not produce an increase in jejunal villous motility when injected intravenously. These data argue against the existence of a humoral stimulant of villous motility (villikinin). Vagotomy caused only a small (20%) and transient (10 min) decline in villous motility. Vagal stimulation at 5, 10, and 20 Hz caused villous motility to increase by 24 .+-. 7, 23 .+-. 9, and 32 .+-. 10%, respectively. Atropine blocked the effects of vagal stimulation. Section of the periarterial (sympathetic) nerves did not alter villous contractile activity. Stimulation of the periarterial nerves at 5, 10, and 20 Hz caused villous contraction frequency to decline by 41 .+-. 5, 45 .+-. 5, and 38 .+-. 10%, respectively. This inhibition appears to involve both .alpha.- and .beta.-adrenergic receptors and a reduction in blood flow. Neither atropine, .alpha.-blockade, nor .beta.-blockade produced a sustained alteration in basal contraction frequency.

(PDF same-day service: $19.90)

Accession: 001893080

Download citation: RISBibTeXText

PMID: 3407775

DOI: 10.1152/ajpgi.1988.255.2.G162

Related references

Neurohumoral control of gastrointestinal motility. Reproduction, Nutrition, Developpement 20(4b): 1125-1141, 1980

Neurohumoral control of colonic motility in the rabbit. American Journal of Physiology 245(4): G582-G588, 1983

Neurohumoral control of gallbladder motility in healthy subjects and diabetic patients with or without autonomic neuropathy. Digestive Diseases & Sciences 35(9): 1089-1097, 1990

Neurohumoral relationships in interoceptive and exteroceptive reflexes Neurohumoral mechanisms in the control of functions. Neurohumoral relationships in interoceptive and exteroceptive reflexes Neurohumoral mechanisms in the control of functions Neirogumoral'nye vzaimootnosheniya pri interotseptivnykh i eksterotseptivykh refleksakh In-Neirogumoral'nye mekhanizmy regulyatsii funktsii Neurohumoral mechanisms in the control of functions 132-142, 1965

Neurohumoral mechanism of leukocyte motility. Deutsche Medizinische Wochenschrift 79(22): 900-901, 1954

Neurohumoral regulation of colonic motility. Surgical Forum 44(0): 147-149, 1993

Nervous and neurohumoral regulation of intestinal motility. Nervous and neurohumoral regulation of intestinal motility, Interscience Publishers, Inc., New York and London, ix + 129. Price: 38s,, 1949

Neurohumoral regulation of Fallopian tube motility. Medicinski Pregled 48(11-12): 395-398, 1995

Neurohumoral regulation of motility and blood flow in the colon. Experientia 28(12): 1447-1448, 1972

Intestinal villous motility and its regulation. American Journal of Digestive Diseases 10(11): 974-976, 1965

Quantitative assessment of villous motility. American Journal of Physiology 252(2 Pt 1): G250-G256, 1987

Interactions between intestinal villous motility and lymph flow. Federation Proceedings 46(3): 683, 1987

Villous motility and unstirred water layers in canine intestine. American Journal of Physiology 258(2 Pt 1): G238-G246, 1990

Effect of various gastrointestinal hormones and vasoactive substances on villous motility. Comparative Biochemistry and Physiology. A, Comparative Physiology 46(1): 171-181, 1973