+ Translate

Neurohumoral control of villous motility

, : Neurohumoral control of villous motility. American Journal of Physiology 255(2 Pt 1): G162-G167

A quantitative videomicroscopic method was used to examine neurohumoral control of villous motility. Intraduodenal instillation of saline, 0.4% hydrochloric acid, or acidified predigested food not cause a significant change in villous contraction frequency in an isolated segment of jejunum. Villous motility in the jejunum of fed dogs, from which the chyme had been removed, was not greater than that in fasted dogs (2.9 .+-. 0.3 vs 3.4 .+-. 0.5 contractions/min). Furthermore, acid extracts of the duodenal mucosa did not produce an increase in jejunal villous motility when injected intravenously. These data argue against the existence of a humoral stimulant of villous motility (villikinin). Vagotomy caused only a small (20%) and transient (10 min) decline in villous motility. Vagal stimulation at 5, 10, and 20 Hz caused villous motility to increase by 24 .+-. 7, 23 .+-. 9, and 32 .+-. 10%, respectively. Atropine blocked the effects of vagal stimulation. Section of the periarterial (sympathetic) nerves did not alter villous contractile activity. Stimulation of the periarterial nerves at 5, 10, and 20 Hz caused villous contraction frequency to decline by 41 .+-. 5, 45 .+-. 5, and 38 .+-. 10%, respectively. This inhibition appears to involve both .alpha.- and .beta.-adrenergic receptors and a reduction in blood flow. Neither atropine, .alpha.-blockade, nor .beta.-blockade produced a sustained alteration in basal contraction frequency.

(PDF 0-2 workdays service)

Accession: 001893080

PMID: 3407775

Submit PDF Full Text: Here

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Related references

Rozé, C., 1980: Neurohumoral control of gastrointestinal motility. The progress of gastrointestinal physiology is presently dominated by the concept of neuroendocrine regulation and the control of motility is in keeping with this concept. Progress in biochemistry, immunocytochemistry and radioimmunoassay in the p...

Snape, W.J.; Shiff, S., 1983: Neurohumoral control of colonic motility in the rabbit. Colonic motility was examined in the proximal (taeniated) and distal (nontaeniated) colon of New Zealand White rabbits. Colonic myoelectric and contractile activities were recorded by bipolar electrodes and extraluminal strain gauges sewn on the a...

Fiorucci S.; Bosso R.; Scionti L.; Disanto S.; Annibale B.; Delle Fave G.; Morelli A., 1990: Neurohumoral control of gallbladder motility in healthy subjects and diabetic patients with or without autonomic neuropathy. Patients affected by diabetes mellitus are reported to have an increased incidence of gallbladder abnormalities. The pathophysiologic mechanisms for this phenomenon are unclear. In the present study ultrasound was used to determine gallbladder emp...

Bulygin, I.A., 1965: Neurohumoral relationships in interoceptive and exteroceptive reflexes Neurohumoral mechanisms in the control of functions. Review. Interoceptive and exteroceptive reflexes are followed by various specific and nonspecific humoral-chemical changes. These neurohumoral changes act not only on the efferent systems and their associated functioning organs but also on the aff...

Fuhrus, C.; Seitz, W., 1954: Neurohumoral mechanism of leukocyte motility. Deutsche Medizinische Wochenschrift 79(22): 900-901

Vernava, A.M.I.i; Longo, W.E.; Carter, J.D.; Chandel, B.; Niehoff, M.; Deshpande, Y.; Standeven, J.; Phillips, R.; Kaminski, R.L., 1993: Neurohumoral regulation of colonic motility. Surgical Forum 44(0): 147-149

Youmans, W.B., 1949: Nervous and neurohumoral regulation of intestinal motility. One cannot avoid the feeling that the physiology of the gastro-intestinal tract has failed in recent years to show the dramatic advances in knowledge characteristic of so many other branches of physiology. This shin little book summarises in admir...

Janković, S.M.; Protić, B.A., 1995: Neurohumoral regulation of Fallopian tube motility. Motility of Fallopian tubes is essential for transport of ova from peritoneal cavity uterus. Numerous substances were found to affect motility of the tubes. Catecholamines cause both relaxation and contraction isolated Fallopian tubes; it depends...

Fasth, S.; Hultén, L., 1972: Neurohumoral regulation of motility and blood flow in the colon. Experientia 28(12): 1447-1448

Kokas, E., 1965: Intestinal villous motility and its regulation. American Journal of Digestive Diseases 10(11): 974-976