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Sympathetic activity and food intake of rats with ventromedial hypothalamic lesions


International Journal of Obesity 12(4): 285-291
Sympathetic activity and food intake of rats with ventromedial hypothalamic lesions
In female Sprague-Dawley rats, 8 to 10 weeks old and 210 to 230 g, with ventromedial hypothalamic (VMH) lesions, feed intake increased from 60 to slightly more than 77 kcal daily during the first 6 days after surgery. Body weight increased and sympathetic activity, as measured by the electrical firing rate of efferent nerves to interscapular brown adipose tissue, decreased significantly.


Accession: 001962140

PMID: 3198309



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