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Synergistic effects of ketoconazole and SF-86327 on the proliferation of epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi


, : Synergistic effects of ketoconazole and SF-86327 on the proliferation of epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi. Annals of the New York Academy of Sciences 544: 357-358

Proliferation of epimastigotes of T. cruzi in LIT medium at 28 degrees C was immediately arrested by ketoconazole or SF-86327 at concentrations <more or => 3 x 10-5 M. SF-86327 stopped cell growth at 10-6 M after 48 h and ketoconazole at 3 x 10-6 M stopped cell growth after 120 h.

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Accession: 001962336

DOI: 10.1111/j.1749-6632.1988.tb40421.x

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