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Synergistic stimulation of prostaglanding E2 production by calcium ionophore and protein kinase C activator in rat granulosa cells


, : Synergistic stimulation of prostaglanding E2 production by calcium ionophore and protein kinase C activator in rat granulosa cells. Biology of Reproduction 40(5): 1000-1006

The effects of LHRH and its putative intracellular mediators on progesterone (P) and PGE2 formation were studied in rat granulosa cells. A calcium ionophore (A23187), 12-O-tetradecanoylphorbol-13-acetate (TPA), and melittin (a phospholipase A2-stimulator) were used to enhance intracellular calcium, protein kinase C and arachidonic acid concentrations resp.

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Schmitz, K.Jürgen.; Lang, H.; Wohlschlaeger, J.; Reis, H.; Sotiropoulos, G.Charalambos.; Schmid, K.Werner.; Baba, H.Andreas., 2006: Elevated expression of cyclooxygenase-2 is a negative prognostic factor for overall survival in intrahepatic cholangiocarcinoma. The production of prostaglandins is regulated by cyclooxygenases (COXs), which also have a role in tumour development and progression in various human malignancies, including cholangiocarcinoma. Limited information is available of the correlation...

Florin, E.L.dwig; Hoerber, H.; Jena, B.P., 1999: Swelling of secretory vesicles. Molecular Biology of the Cell 10(SUPPL ): 84a, Nov

Seco, E.M.; Fotso, S.; Laatsch, H.; Malpartida, F., 2005: A tailoring activity is responsible for generating polyene amide derivatives in Streptomyces diastaticus var. 108. We recently characterized rimocidin B (3b) and CE-108B (4b) as two polyene amides with improved pharmacological properties, produced by genetically modified Streptomyces diastaticus var. 108. In this work, genetic and biochemical analysis of the p...

Chou, W.; Salamon, G.; Orr, N.B.; Salamon, N., 2009: Neuroanatomic analysis of diffusion tensor imaging of white matter tracts with dejerine sections and neuroimaging. We present a neuroanatomical comparison with stereotaxic precision correlating modern diffusion tensor imaging (DTI), MRI data and classical neuroanatomical textbooks. The neuroatlas compiled by J. and A. Dejerine deserves emphasis for its role of...

Kahn, L., 1993: Let us now revisit prepaid group practice. American medicine will soon enter health care reform. The Clinton Administration's Task Force on Health Care Reform is likely to introduce change that relies heavily on managed care, a field now dominated by the health insurance industry. Phy...

Ishizuka, Y.; Hayakawa, Y., 1951: Resistance of Rice plant to the imochi (Rice blast) disease and its relation to the silica and magnesia contents.. At the Hokkaido University, Sapporo, Japan, rice plants cultured in a standard nutrient solution, with the addition of (1) magnesium oxide and silicon dioxide, (2) magnesium oxide alone, (3) silicon dioxide alone, and (4) neither compound, were in...

Jung L.M., 1986: Therapeutic use of digitalis until the time of william withering. Erdmann, E , K Greef And J C Skou (Ed ) Cardiac Glycosides 1785-1985: Biochemistry, Pharmacology, Clinical Relevance; Boehringer Mannheim International Symposia Xvii+552p Steinkopff Verlag Darmstadt: Darmstadt, West Germany; Springer-Verlag: New York, New York, Usa Illus 17-18

Akmaz, A.; Akcapnar, H., 1990: The effects of various levels of nutrition before mating and at late pregnancy on the reproductive performance of Konya Merino ewes and growth and survival rates of their lambs. From 3 weeks before mating, 135 Konya Merino ewes, 4, 5 and 6 years old, grazing low quality pasture, were given lucerne hay 700 g for 4 weeks. Groups A was unsupplemented, groups B and C received concentrates 400 and 800 g each daily, respectivel...

Yu, T-C.; Lay, T-Y., 1989: Morphological comparisons between the progeny, (cold-shocked or othenuise), of self-cross Ctenopharyngodon idella and of its cross with Hypophthalmichthys nobilis, Cyprinus carpio (mirror carp) and Megalobrama amblycophala. Bulletin of Taiwan Fisheries Research Institute, 46: 207-213

Gibbons, R.D.; Dorus, E.; Ostrow, D.G.; Pandey, G.N.; Davis, J.M.; Levy, D.L., 1984: Mixture distributions in psychiatric research. This paper describes the application of Gaussian mixture distributions to biological marker research in psychiatry. Mixtures of univariate and multivariate normal distributions can be used to determine if diagnostically similar psychiatric patient...