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Synthesis and NMR analysis of new natural trichothecenes


, : Synthesis and NMR analysis of new natural trichothecenes. Journal of Natural Products 50(5): 953-957

The major metabolite produced on culturing a Canadian isolate of Fusarium sporotrichioides was T-2 toxin; in addition some 16 minor compounds were isolated.

Accession: 001962400

DOI: 10.1021/np50053a035

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Related references

Davis N.D.; Whidden M.P.; Diener U.L., 1976: Multiple analysis for myco toxins in natural products part 2 ochra toxin rubra toxin zearalenone and trichothecenes. Journal of the Alabama Academy of Science 47(3): 118

Scott, P.M., 1989: The natural occurrence of trichothecenes. The worldwide occurrence of trichothecene mycotoxins in grains, feeds and certain other commodities is summarized. Trichothecene contamination is reported from Asia (including Japan, Korea, China, Taiwan, India, Sri Lanka), Africa, South America,...

Schiefer, H.B.; Hancock, D.S.; Bhatti, A.R., 1986: Systemic effects of topically applied trichothecenes. I. Comparative study of various trichothecenes in mice. T-2 toxin, HT-2 toxin, Diacetoxyscirpenol (DAS), Roridin A, Verrucarin A and 3-Acetyldeoxynivalenol (3-AcDON) were dissolved in dimethyl sulfoxide and applied topically to mice. For a mortality study, groups of 10-20 male mice received either 5, 1...

Kamimura, H., 1984: Trichothecenes - occurrence of trichothecenes in agricultural products and frequency of trichothecene-contaminated kernels. The occurrence o trichothecenes (deoxynivalenol and nivalenol) in commercial foods (popcorn, maize meal, barley) in Japan, their stability after heat treatment and the effect of water soaking on their levels in barley are discussed.

Busby, W.J.; Wogan, G., 1981: Trichothecenes Occurrence, metabolism, nucleic acid synthesis, protein synthesis, structure-activity relationships, mycotoxins. Mycotoxins and N nitroso compounds: environmental risks editor Ronald C Shank: 5

Tseng, T.C., 1983: Natural occurrence of trichothecenes in Taiwan. None of 428 rice samples for human consumption from various districts of Taiwan was found to contain Fusarium mycotoxins (T-2 toxin, diacetoxyscirpenol, deoxynivalenol and zearalenone). Some animal feedstuffs were contaminated with zearalenone but...

Pathre, S.; Mirocha, C., 1979: Trichothecenes: natural occurrence and potential hazard. Journal of the American Oil Chemists' Society 56(9): 820-823

Patterson, D.S.P., 1983: Trichothecenes: toxicoses and natural occurrence in Britain. Following a review of the ltierature it is concluded that trichothecene mycotoxins do not appear to present a major problem in UK; less than 1% of suspected feedstuff samples examined in recent years have contained detectable quantities of T-2 tox...

Anderson, D.W.; Ashton, P.R.; Black, R.M.; Leigh, D.A.; Slawin, A.M.Z.; Stoddart, J.F.aser; Williams, D.J., 1988: The complexation properties of some unnatural and natural macrocyclic trichothecenes. Journal of the Chemical Society, Chemical Communications 13: 904

Pathre, S.; Mirocha, C., 1977: Assay method for trichothecenes and review of their natural occurrence. Mycotoxins in Human and Animal Health: 29-253