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Synthesis and antifungal activities of 1-p-methyl- alpha -benzylazoles and some related products






Archiv der Pharmazie Weinheim 322(6): 369-373

Synthesis and antifungal activities of 1-p-methyl- alpha -benzylazoles and some related products

The synthesis and antifungal activities against Candida albicans and Candida spp. (C. glabrata, C. guilliermondii, C. tropicalis, C. pseudotropicalis C. lipolytica, C. parapsilosis, C. krusei, C. viswanathii and C. inconspicua) of some pyrrole analogues of bifonazole are reported. 1-{p-Methyl- alpha -(4-(1H-pyrrol-1-yl)phenyl)benzyl}imidazole was found to be equipotent or sometimes superior to bifonazole and ketoconazole and slightly inferior to miconazole.


Accession: 001962412



Related references

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