+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Synthesis of macrocyclic trichothecene mycotoxins

, : Synthesis of macrocyclic trichothecene mycotoxins. Tetrahedron 45(8): 2385-2416

In the first part synthetic approaches and total syntheses of the trichothecenes are summarized. Special attention is paid to not naturally occurring derivatives of the sesquiterpenoids. In the second part the syntheses of macrocyclic trichothecenes are reviewed, with special reference to the preparation of the macrolidic building blocks, protecting groups and methods of macrolactonization. The preparation of several new unnatural macrocyclic analogues is reported. Finally the biological activity of the simple and macrocyclic trichothecenes are briefly discussed.

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 001962587

DOI: 10.1016/s0040-4020(01)83438-4

PDF Full Text: Synthesis of macrocyclic trichothecene mycotoxins

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Assoumani, M.B.; Nguyen, N.P., 1991: Enzyme modelling of protein digestion and L-lysine availability. The potential use of an alpha -L-lysine oxidase electrode to monitor the impact of microwave heat treatment on early Maillard reactions in whole soyabeans to assess lysine availability is considered. The method gave data consistent with published...

Poland, G.A.; Jacobson, R.M.; Ovsyannikova, I.G., 2009: Influenza virus resistance to antiviral agents: a plea for rational use. Although influenza vaccine can prevent influenza virus infection, the only therapeutic options to treat influenza virus infection are antiviral agents. At the current time, nearly all influenza A/H3N2 viruses and a percentage of influenza A/H1N1 v...

Maizels N.; Bothwell A., 1985: The t cell independent immune response to the hapten 4 hydroxy 3 nitrophenylacetyl uses a large repertoire of heavy chain genes. Hybridomas generated from C57BL/6 mice immunized with the hapten NP coupled to ficoll, a T-cell-independent carrier, produce monoclonal antibodies that use a large repertoire of VH regions and light chains. This contrasts with the homogeneity of t...

Batra, L.R., 1994: Edith Katherine Cash, 1890- 1992. Mycologia 86: 4-7

Eagleson, P.S.; Shack, W.J., 1966: Some criteria for the measurement of rainfall and runoff. Techniques of linear analysis are used to study urban and rural drainage basins as low-pass filters. The frequency passband of the basin is determined in terms of its physical characteristics. This determination is used, in conjunction with the sp...

Steiner, A.; Bolte, A.; Schneider, B.U.; Huttl, R.F., 1998: Phytomass and nutrient content of different nitrogen influenced Scots pine stands (Pinus sylvestris L.) in the northeastern lowland of Germany. Phytomass and nutrient partitioning were studied in two Scots pine (Pinus sylvestris) stands of the German northeastern lowland at Hubertusstock/Schorfheide (low N-deposition) and Bayerswald/Schwedt (high N-deposition). The total tree phytomass wa...

Conklin, B.R.; Chabre, O.; Wong, Y.H.; Federman, A.D.; Bourne, H.R., 1992: Recombinant Gq alpha. Mutational activation and coupling to receptors and phospholipase C. Gq mediates hormonal stimulation of phosphoinositide-specific phospholipase C (PI-PLC). We mutated the alpha subunit of Gq (alpha q) to replace arginine 183 with cysteine. Mutations that substitute cysteine for the corresponding arginine residues...

Mahrer Kenneth D., 1984: Approximating surface deformation from a buried strike-slip fault or shear crack in a mildly uneven half-space. A mathematical method for approximating the elastostatic surface deformation fields (strains and displacements) produced by a buried strike-slip fault or long shear crack in a mildly uneven, homogeneous elastic half-space. The approximation scheme...

Grand, A.; Glaizal, S.; Caudie, C.; Schrive, I.; Matas, O.; Fichter, P.; Shibli, H., 1990: Serum myoglobin assay in the early phase of myocardial infarction treated with intravenous streptokinase. Presse Medicale 19(15): 720-720

Costanzo, S.; Caserta, P.; Nazzaro, A., 2005: Terrorism and terrorist. Forensic Science International 146 Suppl: S189-S190