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Synthetic antifungal drugs


, : Synthetic antifungal drugs. Vestnik Dermatologii i Venerologii (10): 26-32

The antifungal drugs reviewed include triazoles, and derivatives of imidazoles, pyridine and pyrimidine, of aromatic, aliphatic and organic acids, and of phenols.

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Related references

Anonymous, 1953: Studies on antifungal substances I Comparison of antifungal activities of some synthetic drugs

Pinault, L.C.estian, J., 1978: Antifungal veterinary drugs. 1. Synthetic substances. Recueil de medecine veterinaire: 154 (5) 419-424

Datry, A.; Thellier, M.; Traore, B.; Cisse, O.A.; Danis, M., 2001: Antifungal drugs in the treatment of systemic candidiosis: susceptibility to antifungal drugs, viewpoint on drug resistance, pharmacological data. This article describes the drugs available for treating systemic candidosis (amphotericin B, flucytosine, fluconazole, itraconazole and ketoconazole): their pharmacology, testing of sensitivity (there is no reliable standard method), the use of dr...

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Dikstein, S., 1970: Antifungal drugs for oculomycosis. 3. In vitro measurement of corneal endothelial toxicity of certain antifungal drugs. The toxicity of the drugs was measured and divided by the min. fungistatic conc. to give the ' therapeutic index '. Where this was >1 the drug was considered of possible value for therapy. Results indicated that 5-fluorocytosine and s...

Dikstein, S., 1970: Antifungal drugs for oculomycosis: III. In vitro measurement of corneal endothelial toxicity of certain antifungal drugs. The toxicity of the drugs was measured and divided by the min. fungistatic conc. to give the ' therapeutic index '. Where this was >1 the drug was considered of possible value for therapy. Results indicated that 5-fluorocytosine and s...

Richards, A.B.; Clayton, Y.M.; Jones, B.R., 1970: Antifungal drugs for oculomycosis. IV. The evaluation of antifungal drugs in the living animal cornea. A method of producing a large number of reproducible lesions by inoculating tenfold dilutions of a fungal suspension into multiple sites in the cornea is described. From the data the 50 % corneal infection dilution can be calculated and titres in...

Macura, A.B.; Dwernicka, B., 1989: Effect of synthetic antifungal drugs on the adherence of Candida albicans to the mouth mucosa epithelium in vitro. Ten Candida albicans strains were tested for their adherence to buccal epithelial cells in vitro in the presence of synthetic antimycotic drugs as 5-fluorocytosine, clotrimazole and ketoconazole. The drugs when applied in therapeutic concentration...

Anonymous, 1988: Antifungal drugs. First International Conference on Drug Research in Immunological and Infectious Diseases. Antifungal Drugs: Synthesis, Preclinical and Clinical Evaluation held in Garden City, New York, USA, October 8-10, 1987. Papers presented at this conference are included in sections on: design, synthesis, and structure-activity relationships of antifungal agents; structural elucidation, synthesis, and antifungal activity of natural products and related derivatives;...

Matusevicius,A.; Ivaskiene,M.; Spakauskas,V.; Daunoras,G., 2008: Part II Antifungal drugs, antifungal substance, compounds and drugs Review. The incidence of fungal infections has increased worldwide. The need for new antifungal agents has arisen largely through the increase in numbers of fungal infections. Relatively few agents are available for treatment of mycoses, e.g. amphotericin...