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The effects of paraquat on microsomal oxygen reduction and antioxidant defenses in ribbed mussels (Geukensia demissa) and wedge clams (Rangia cuneata)



The effects of paraquat on microsomal oxygen reduction and antioxidant defenses in ribbed mussels (Geukensia demissa) and wedge clams (Rangia cuneata)



Marine Environmental Research 24(1-4): 301-305



The hepatopancreae of the ribbed mussel, Geukensia demissa, and the wedge clam, Rangia cuneata, were examined for their ability to catalyze the reduction/oxidation cycling of paraquat. In vitro studies indicated a dose-dependent increase in the rate of superoxide anion (O2-) generation in microsomal fractions supplemented with NADPH; the highest concn of paraquat employed (4 mM) elicited an 81% increase in chytochrome c reduction in G. demissa and a 135% increase in R. cuneata.

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Accession: 001974306

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DOI: 10.1016/0141-1136(88)90325-x


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