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Vaccine efficacy and innocuity of strain 783 of Aujeszky's disease virus

Vaccine efficacy and innocuity of strain 783 of Aujeszky's disease virus

Vaccination and control of Aujeszky' s Disease: 27-35

A glycoprotein 1 (gl) and thymidine kinase (TK) deletion mutant of the Aujeszky's disease virus (ADV) strain NIA-3 was constructed. The mutant, designated ADV 783, was examined for vaccine efficacy and safety. A single i/m vaccination of seronegative pigs with 105 plaque-forming units (PFU) of ADV strain 783 conferred almost complete protection against challenge with 105 PFU of virulent ADV, 12 weeks after vaccination.

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