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Can the response to interferon treatment be predicted in patients with chronic active hepatitis C?

Australian and New Zealand Journal of Medicine 21(3): 387-392

Can the response to interferon treatment be predicted in patients with chronic active hepatitis C?

Chronic hepatitis C infection can be suppressed by alpha -interferon, and about 20% of patients will be cured by 6 or more months' therapy. In this study of such treatment, response in terms of both short-term reduction of aminotransferase activity and long-term remission was most likely in those with mild liver disease and after acquisition by drug abuse rather than other sources. This contrasts with hepatitis B where responders generally have more severe liver disease.M.G.

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Accession: 002042369

PMID: 1953524

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