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Candida albicans and three other Candida species contain an elongation factor structurally and functionally analogous to elongation factor 3


FEMS Microbiology Letters 80(1): 45-49
Candida albicans and three other Candida species contain an elongation factor structurally and functionally analogous to elongation factor 3
A cell-free poly(U)-dependent translation elongation system from Candida albicans is ATP-dependent due to the presence of an elongation factor 3 (EF3)-like activity. Saccharomyces cerevisiae ribosomes added to a C. albicans postribosomal supernatant (PRS) supported poly(U)-dependent elongation, suggesting that the C. albicans lysate contained a soluble translation factor functionally analogous to the S. cerevisiae translation factor EF-3. The presence of EF-3 in C. albicans was confirmed by Western blotting using an antibody raised against S. cerevisiae EF-3. This antibody was also used to screen a selection of Candida species, all of which possessed EF-3 with molecular mass in the range of 110-130 kDa.

Accession: 002042454

PMID: 1855649

DOI: 10.1111/j.1574-6968.1991.tb04634.x

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Related references

Candida albicans and three other Candida species contain an elongation factor structurally and functionally analogous to elongation factor 3. Fems Microbiology Letters 64(1): 45-49, 1991

Candida albicans and three other candida spp contain an elongation factor structurally and functionally analogous to elongation factor 3. FEMS Microbiology Letters 80(1): 45-50, 1991

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