+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Cantharidin-induced acantholysis

Cantharidin-induced acantholysis

American Journal of Dermatopathology 10(5): 419-423

Cantharidin (0.1% in DMSO) was used to induce acantholysis by topical application to the forearms of volunteers. Intraepidermal clefting started at the junction between the basal and epidermal layers, and later involved all of the levels of the stratum spinosum. As a response to early acantholysis, an increased number of epibasal cells synthesized DNA. This was not related to an increased binding of epidermal growth factor to these cells.

(PDF same-day service: $19.90)

Accession: 002042697

Download citation: RISBibTeXText

PMID: 3228189

DOI: 10.1001/archderm.1966.01600280127020

Related references

Cantharidin-induced acantholysis in Darier's disease: Does acantholysis initiate dyskeratosis?. British Journal of Dermatology 131(1): 40-47, 1994

An electron microscopic study of cantharidin-induced acantholysis. Acta Dermatologica-Kyoto. English Edition 63(3): 289-294, 1968

Cantharidin-induced acantholysis. Dependence on epidermal respiration. Archives of Dermatology 94(4): 509-513, 1966

Phospho lipids and cantharidin induced acantholysis in human epidermis. J Invest Dermatol 47(6): 606-607, 1966

Plasminogen, adhesion molecules and related proteins in cantharidin induced acantholysis. British Journal of Dermatology 127(4): 427, 1992

Cantharidin-induced acantholysis: Adhesion molecules, proteases, and related proteins. British Journal of Dermatology 130(2): 148-157, 1994

The nature of cantharidin acantholysis. Journal of Investigative Dermatology 33: 287-292, 1959

The mechanism of cantharidin acantholysis. Journal of Investigative Dermatology 39: 39-45, 1962

Mechanism Of Acantholysis: The Effect Of Cantharidin On Oxidative Phosphorylation. Journal of Investigative Dermatology 42: 465-469, 1964

Effect of magnesium ions on acantholysis produced artificially in vitro with the aid of cantharidin. Przeglad Dermatologiczny 49(Suppl): 59-61, 1962

An adaptation of the Lineweaver-Burks graphical method to the hlsto-chemical system of phosphorylase in cantharidin acantholysis. Tohoku J Exp Med: 397-404, 1965

Acantholysis produced in vitro with pemphigus serum: hydrocortisone inhibits acantholysis, while dapsone and 6-mercaptopurine do not inhibit acantholysis. Journal of Clinical Immunology 4(5): 359-363, 1984