EurekaMag.com logo
+ Site Statistics
References:
53,623,987
Abstracts:
29,492,080
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Differential cholecystokinin gene expression in brain and gut of the fasted rat



Differential cholecystokinin gene expression in brain and gut of the fasted rat



American Journal of the Medical Sciences 299(1): 32-37



Cholecystokinin (CCK) gene expression has been compared in the brain and duodenum of control and 5 days fasted rats. To study transcription, CCK mRNA was quantified using a solution hybridization assay. Large and small molecular weight CCK peptides were separated using a sequential extraction process and subsequently quantified by radioimmunoassay. In the duodenum, a fall in weight was paralleled by a decrease in CCK mRNA and in the large forms of CCK peptides. Small molecular species of CCK peptides did not change. There was no change in weight, CCK transcriptional or translational products in the brain as a whole. These data indicate location-specific differential regulation of the products of CCK gene expression in the fasted rat.

(PDF same-day service: $19.90)

Accession: 002072529

Download citation: RISBibTeXText

PMID: 2296995

DOI: 10.1097/00000441-199001000-00008



Related references

Differential regulation of cholecystokinin gene expression occurs in brain and gut of the fasted rat. Clinical Research 36(3): 396A, 1988

Differential expression of the mouse cholecystokinin gene during brain and gut development. Proceedings of the National Academy of Sciences of the United States of America 82(17): 5593-5597, 1985

Brain cholecystokinin in fasted and fed mice. Life Sciences 26(12): 969-970, 1980

Cholecystokinin gene related peptides distribution and characterization of immunoreactive pro cholecystokinin and an amino terminal pro cholecystokinin fragment in rat brain. Brain Research 344(2): 351-355, 1985

Differential regulation of pancreatic digestive enzyme gene expression by cholecystokinin. Gastroenterology 94(5 PART 2): A386, 1988

Effect of cholecystokinin on gene expression in the rat brain. Society for Neuroscience Abstracts 17(1-2): 974, 1991

Expression of the cholecystokinin gene in rat brain during development. Developmental Neuroscience 9(1): 61-67, 1987

Regional variations in cholecystokinin gene expression in the rat brain. Society for Neuroscience Abstracts 12(2): 1458, 1986

Differential expression of gastrin, cholecystokinin-A and cholecystokinin-B receptor mRNA in human pancreatic cancer cell lines. Scandinavian Journal of Gastroenterology 36(7): 738-743, July, 2001

Effect of cholecystokinin on expression of immediate early gene mrnas in the rat brain. Japanese Journal of Pharmacology 59(SUPPL 1): 147P, 1992

Differential regulation of psychostimulant-induced gene expression of brain derived neurotrophic factor and the immediate-early gene Arc in the juvenile and adult brain. European Journal of Neuroscience 29(3): 465-476, 2009

Regulation of mouse cholecystokinin gene expression in brain and small intestine. Gastroenterology 94(5 PART 2): A136, 1988

Gene expression profiling in postmortem rett syndrome brain Connecting differential gene expression to functional biology. Society for Neuroscience Abstracts 27(2): 1784, 2001

Gene expression profiling in postmortem Rett Syndrome brain: differential gene expression and patient classification. Neurobiology of Disease 8(5): 847-865, 2001