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Differential development of tolerance to the effects of d-amphetamine and fenfluramine on food intake in baboons



Differential development of tolerance to the effects of d-amphetamine and fenfluramine on food intake in baboons



Journal of Pharmacology and Experimental Therapeutics 252(3): 960-969



Food intake of 6 adult male baboons (Papio cynocephalus anubis) was monitored during daily 22-h experimental sessions. Food was available in a chain schedule with 2 components. After completion of the first "procurement component" response requirement, access to food, i.e., a meal, became available under the second "consumption component," during which each response produced a 1-g food pellet. After a 10-min interval in which no response occurred, the consumption component was terminated.

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Accession: 002072545

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PMID: 2319478



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