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Differential production of granulocyte-macrophage colony-stimulating factor by macrophages from mice susceptible and resistant to Leishmania mexicana amazonensis

Differential production of granulocyte-macrophage colony-stimulating factor by macrophages from mice susceptible and resistant to Leishmania mexicana amazonensis

Journal of Leukocyte Biology 51(3): 220-224

Macrophages from mice susceptible to infection with L. amazonensis were shown to sustain a higher production of granulocyte-macrophage colony-stimulating factor (GM-CSF) throughout the in vitro infection than macrophages from a resistant strain. Resident macrophages from BALB/c and C57B1/10 mice were infected with promastigotes of L. amazonensis and the amount of biologically active GM-CSF was measured in the supernatants collected at different times of infection.

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Accession: 002072726

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PMID: 1541906

DOI: 10.1002/jlb.51.3.220

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