+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Effect of different tumor types on resting energy expenditure

Effect of different tumor types on resting energy expenditure

Cancer Research 51(22): 6138-6141

The purpose of this study was to investigate whether the presence of a malignant tumor influences energy metabolism of the host. Resting energy expenditure (REE) was measured in 104 gastric and colorectal (GCR) cancer patients and in 47 non-small cell lung cancer patients and was compared with REE values in 40 healthy controls. REE expressed per kilogram of fat-free mass (FFM) in lung cancer patients was elevated, in comparison with healthy controls (33.6 +/- 4.6 and 29.6 +/- 2.9 kcal, respectively; P less than 0.001), in contrast to REE/FFM in GCR cancer patients, which showed no difference, compared with these controls (29.8 +/- 4.3 kcal). In 47 patients with GCR cancer and in 14 patients with lung cancer, REE was also determined after tumor resection. REE in GCR cancer patients measured 1.5 years after tumor resection showed a small but significant increase. No differences were observed between GCR cancer patients with or without signs of tumor recurrence. REE in lung cancer patients with no signs of tumor recurrence measured 1 year after tumor resection had a significant decrease in REE (REE/FFM, -6.8%; P less than 0.05), while patients who had evidence of tumor recurrence showed no change in REE or even an increase. After curative surgery REE returned to a normal level in the lung cancer patients. These results suggest that tumor type is a major determinant of an increased energy expenditure in cancer patients.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 002081743

Download citation: RISBibTeXText

PMID: 1657379

Related references

The effects on resting energy expenditure of different tumor types. Cancer 58(8): 1739-1744, 1986

Re: Comparison of resting energy expenditure prediction methods with measured resting energy expenditure in obese, hospitalized adults. Jpen. Journal of Parenteral and Enteral Nutrition 33(6): 735-736, 2010

Comparison of resting energy expenditure prediction methods with measured resting energy expenditure in obese, hospitalized adults. Jpen. Journal of Parenteral and Enteral Nutrition 33(2): 168-175, 2009

World Health Organization equations have shortcomings for predicting resting energy expenditure in persons from a modern, affluent population: generation of a new reference standard from a retrospective analysis of a German database of resting energy expenditure. American Journal of Clinical Nutrition 80(5): 1379-1390, 2004

Sex hormone suppression reduces resting energy expenditure and {beta}-adrenergic support of resting energy expenditure. Journal of Clinical Endocrinology and Metabolism 90(6): 3312-3317, 2005

Intra- and interindividual variability of resting energy expenditure in healthy male subjects -- biological and methodological variability of resting energy expenditure. British Journal of Nutrition 94(5): 843-849, 2005

Resting energy expenditure, activity energy expenditure and total energy expenditure at age 91-96 years. British Journal of Nutrition 84(3): 319-324, 2000

Interleukin-1-beta and tumor necrosis factor-alpha reduce energy intake and elevate resting energy expenditure in rheumatoid arthritis. FASEB Journal 7(3-4): A725, 1993

Changes in resting energy expenditure (REE) as a function of tumor response to sunitinib in a cachexic patient with a metastatic endocrine tumor of the pancreas. Acta Oncologica 49(8): 1390-1391, 2010

Spinal Muscular Atrophy, types I and II: What are the differences in body composition and resting energy expenditure?. Clinical Nutrition 36(6): 1674-1680, 2017

Energy Expenditure After Liver Resection: Validation of a Mobile Device for Estimating Resting Energy Expenditure and an Investigation of Energy Expenditure Change After Liver Resection. Jpen. Journal of Parenteral and Enteral Nutrition 41(5): 766-775, 2017

Total daily energy expenditure relative top resting energy expenditure in clinically stable patients with COPD. Thorax 52(9): 780-785, 1997

Prediction of daily energy expenditure during a feeding trial using measurements of resting energy expenditure, fat-free mass, or Harris-Benedict equations. American Journal of Clinical Nutrition 80(4): 876-880, 2004

Measured resting energy expenditure vs estimated energy expenditure by formula in overweight or obese children. International Journal of Obesity 22(Suppl. 3): S156, 1998