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Haematological and pathological responses to experimental Trixacarus caviae infection in guinea pigs



Haematological and pathological responses to experimental Trixacarus caviae infection in guinea pigs



Journal of Comparative Pathology 104(2): 179-185



Outbred guinea pigs became infected with the mite Trixacarus caviae (Acarina, Sarcoptidae) when introduced into an infected colony. Mite numbers were highest after one month, then fell progressively. Infected guinea pigs developed a neutrophilia, monocytosis, eosinophilia and basophilia. Despite pronounced reactive changes in the superficial lymph nodes, infected guinea pigs developed only a mild dermatitis. In contrast, home bred animals, susceptible to T. caviae acquired many mites and developed a severe chronic dermatitis. Trixacaral manage in guinea pigs offers considerable potential for the study of mite infections in man and animals.

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Accession: 002122948

Download citation: RISBibTeXText

PMID: 1865027

DOI: 10.1016/s0021-9975(08)80101-6



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