Section 3
Chapter 2,147

Isolation of Staphylococcus hyicus subsp. hyicus from pigs affected with exudative epidermitis and experimental infection of piglets with isolates

Sato, H.; Tanabe, T.; Nakanowatari, M.; Oyama, J.; Yamazaki, N.; Yoshikawa, H.; Yoshikawa, T.; Koyama, H.; Saito, H.

Kitasato Archives of Experimental Medicine 63(2-3): 119-130


ISSN/ISBN: 0023-1924
PMID: 2096257
Accession: 002146279

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Five strains of S. hyicus subsp. hyicus were isolated: 3 strains (P-1, P-2 and P-3) from the crust on the body surface of 6-month-old pigs on a farm in Aomori prefecture, and 2 (P-5 and P-6) from both the crust on the body surface and the joint of a 1-month-old piglet with exudative epidermitis (EE) on another farm. The characterization of the isolates and the experimental infection of the piglets with strain P-1 were carried out. Subcutaneous inoculation with the bacterial suspension (1010 CFU) produced EE in all 9 piglets. Eight of them had exudation and exfoliation within 24 h of infection. Histopathologically, disappearance of stratum corneum and necrosis with vacuolar degeneration of prickle cells were pronounced in the epidermis.

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