+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn

+ Translate
+ Recently Requested

Mode of action of delta-endotoxins from Bacillus thuringiensis: a comparison with other bacterial toxins

Mode of action of delta-endotoxins from Bacillus thuringiensis: a comparison with other bacterial toxins

Insect Biochemistry and Molecular Biology 22(1): 1-7

Delta-endotoxins are a class of insecticidal proteins produced by Bacillus thuringiensis. While there are many steps in the mode of action of these toxins, they ultimately interact with the insect midgut epithelium, binding and opening cation-selective channels. Delta-endotoxins form cation-selective channels in planar lipid bilayers, suggesting that these channels are responsible for toxicity. In order to be toxic, the required interaction of delta-endotoxins with the midgut epithelium must create a collection of physical-chemical events necessary for a tight association with the membrane, intercalation into the membrane, and formation of an open channel. These events are discussed in relation to the mode of action of other bacterial toxins.

(PDF emailed within 0-6 h: $19.90)

Accession: 002162189

Download citation: RISBibTeXText

DOI: 10.1016/0965-1748(92)90093-T

Related references

Mode of action of Bacillus thuringiensis delta-endotoxins. Zentralblatt fur Bakteriologie: Supplement: 9) 289-290, 1990

The mode of action of Bacillus thuringiensis endotoxins. Annual Review of Entomology 37: 615-636, 1992

Production of multiple delta-endotoxins by Bacillus thuringiensis: delta-endotoxins produced by strains of the subspecies galleriae and wuhanensis. Canadian Journal of Microbiology 40(12): 1026-1034, 1994

Mechanism of action of Bacillus thuringiensis insecticidal delta -endotoxins. Advances in Insect Physiology 24: 275-308, 1994

Three toxins, two receptors, one mechanism: Mode of action of Cry1A toxins from Bacillus thuringiensis in Heliothis virescens. Insect Biochemistry and Molecular Biology 76: 109-117, 2017

The role of succinate dehydrogenase in bacterial resistance to the delta endotoxins of Bacillus thuringiensis. Mikrobiologiia 74(5): 711-713, 2005

Comparison of Bacillus thuringiensis delta-endotoxins originating from different genes. Zentralblatt fur Bakteriologie Mikrobiologie und Hygiene: 1: Abt: Supplemente: 7) 55-56, 1988

The crystal delta -endotoxins of Bacillus thuringiensis: models for their mechanisms of action on the insect gut. BioEssays 15(7): 469-476, 1993

Genetic and biochemical studies of the mechanism of action of bacillus thuringiensis entomocidal delta endotoxins. Zentralblatt fuer Bakteriologie Supplement 19: 499-506, 1990

Sensitivity of dissociation variants of Micrococcus luteus to the action of delta-endotoxins of Bacillus thuringiensis. Mikrobiologiia 65(3): 365-369, 1996

Mode of action of Bacillus thuringiensis toxins. Chemistry of crop protection: progress and prospects in science and regulation: 213-234, 2003

Mode of action of Cry toxins from Bacillus thuringiensis. TIP Revista Especializada en Ciencias Quimico-Biologicas 5(1): 5-13, Junio, 2002

Bacillus thuringiensis toxins and mode of action. Agriculture Ecosystems & Environment 49(1): 21-26, 1994