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Morphine decreases LH secretion in ovariectomized ewes only after steroid priming and not by direct pituitary action

Horton, R.J.; Li, J.Y.; Cummins, J.T.; Smith, A.I.; Shen, P.J.; Clarke, I.J.

Neuroendocrinology 52(6): 612-617

1990


ISSN/ISBN: 0028-3835
PMID: 2126611
DOI: 10.1159/000125653
Accession: 002164733

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To determine whether opiates directly modulate LH secretion in vivo, morphine was administered to hypothalamo-pituitary-disconnected (HPD) ewes which were also receiving GnRH.

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