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Performance of feedlot steers fed diets containing laidlomycin propionate or monensin plus tylosin, and effects of laidlomycin propionate concentration on intake patterns and ruminal fermentation in beef steers during adaptation to a high-concentrate diet



Performance of feedlot steers fed diets containing laidlomycin propionate or monensin plus tylosin, and effects of laidlomycin propionate concentration on intake patterns and ruminal fermentation in beef steers during adaptation to a high-concentrate diet



Journal of Animal Science 70(10): 2950-2958



Two hundred eighty-eight beef steers (British X Continental X Brahman) were fed a 90% concentrate diet containing either no ionophore (control), laidlomycin propionate at either 6 or 12 mg/kg of dietary DM, or monensin plus tylosin (31 and 12 mg/kg of DM, respectively). Neither of the two levels of laidlomycin propionate nor monensin plus tylosin affected (P > .10) ADG or feed:gain ratio. Monensin plus tylosin reduced (P < .01) daily DMI for the 161-d trial period compared with the other three treatments. Laidlomycin propionate at 6 mg/kg increased (P < .05) DMI relative to the control, laidlomycin propionate at 12 mg/kg, and monensin plus tylosin diets during the 2nd wk of the trial and from d 57 to 84. Treatments did not affect carcass measurements. In a second experiment, 12 ruminally cannulated steers were fed diets containing no ionophore or laidlomycin propionate at either 6 or 12 mg/kg of DM. Samples were obtained for two consecutive days while the dietary concentrate level was 75%, after which the diet was switched abruptly to 90% concentrate, and samples were collected on several days during a 21-d period. The rate at which steers consumed their daily allotment of feed was not altered markedly by laidlomycin propionate. Likewise, laidlomycin propionate did not affect total ruminal VFA concentrations or proportions. Ruminal concentrations of D- lactate were reduced (P < .10) by 6 but not by 12 mg/kg of laidlomycin propionate. Ruminal pH was not affected in a consistent manner by treatments, but 12 mg/kg of laidlomycin propionate increased both peak and overall ruminal ammonia concentration on several sampling days. Results suggest that laidlomycin propionate is as effective as monensin plus tylosin for growing finishing cattle, and that some ruminal changes with laidlomycin propionate depended on the dose that was fed.

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Accession: 002182128

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PMID: 1429270


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