+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Sequence instability and functional inactivation of murine Y chromosomes can occur on a specific genetic background



Sequence instability and functional inactivation of murine Y chromosomes can occur on a specific genetic background



Molecular Biology and Evolution 9(2): 331-365



When the Y chromosome from Mus poschiavinus (YPos) is backcrossed onto the C57BL/6J laboratory strain of mice, testicular dysfunction occurs at a high frequency. When 5 multicopy probes from the recombinationally suppressed region of the Y chromosome were used in the present work, genomic DNAs from sibling progeny of C57BL/6J YPos were found to contain YPos-specific sequences ranging from trace levels to levels consistent with an intact Y chromosome.

(PDF emailed within 1 workday: $29.90)

Accession: 002219012

Download citation: RISBibTeXText

PMID: 1560768


Related references

Genetic instability of specific chromosomes associated with a family history of cancer. Cancer Genetics & Cytogenetics 136(1): 73-77, July 1, 2002

Genetic control over genome instability: the characteristics of genetic instability in a mutator Drosophila line upon substitution of individual chromosomes. Moscow University biological sciences bulletin6(1): 21-26, 1991

Effect of genetic background on functional and cellular responses to Meconium Aspiration in a murine model. Pediatric Research 53(4 Part 2): 484A-485A, 2003

Fv-4: gene controlling resistance to NB-tropic Friend murine leukemia virus. Distribution in wild mice, introduction into genetic background of BALB/c mice, and mapping of chromosomes. Journal of the National Cancer Institute 67(5): 1123-1127, 1981

Genetic and physical mapping of sequence-specific amplified polymorphic (SSAP) markers on the 1RS chromosome arm of rye in a wheat background. Tag. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik 107(7): 1271-1277, 2003

Structural and functional studies of RegB, a new member of a family of sequence-specific ribonucleases involved in mRNA inactivation on the ribosome. Journal of Biological Chemistry 282(3): 2019-2028, 2006

Sequence, genomic organization and functional expression of the murine tRNA-specific adenosine deaminase ADAT1. Gene (Amsterdam) 243(1-2): 59-66, Feb 8, 2000

Genetic functional inactivation of neuronal nitric oxide synthase affects stress-related Fos expression in specific brain regions. Cellular and Molecular Life Sciences 61(12): 1498-1506, 2004

Construction of monochromosomal microcell hybrids containing single murine chromosomes in a rodent background. American Journal of Human Genetics 61(4 SUPPL ): A236, 1997

Genetic instability in myelodysplastic syndrome Microsatellite alterations occur in a substantial portion of patients with MDS. Blood 92(10 SUPPL 1 PART 1-2): 420A, Nov 15, 1998

Centrosome defects and genetic instability occur together in precancerous lesions of the breast, cervix and prostate. Molecular Biology of the Cell 12(Supplement): 175a, 2001

Transfer of murine leukaemia and murine sarcoma virus genetic information by transfection with isolated metaphase chromosomes. Journal of General Virology 62: 227-237, 1982

The functional significance of DNA sequence structure in a site-specific genetic recombination reaction. Embo Journal 7(6): 1845-1852, 1988

Role of genetic background in induced instability. Oncogene 22(45): 6994-6999, 13 October, 2003

Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype. Developmental Cell 16(2): 314-320, 2009