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Serine-rich ultra high sulfur protein gene expression in murine hair and skin during the hair cycle



Serine-rich ultra high sulfur protein gene expression in murine hair and skin during the hair cycle



Journal of Biological Chemistry 265(34): 21375-21380



To study the regulation of hair differentiation, a mouse genomic clone, gUHS-SER-M16, was isolated that contained 2 members of the family of serine-rich ultra high sulphur protein genes. One of the genes, gUHS-SER-1, encodes 230 amino acids with 40% cysteine and 23% serine; the other gene, gUHS-SER-2, encodes 223 amino acids with 41% cysteine and 21% serine. The similarity between the 2 genes is 73%, and both have several 10-amino acid repeats within their coding regions.

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Accession: 002219216

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