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Specific cleavage of pre-edited mRNAs in trypanosome mitochondrial extracts

Specific cleavage of pre-edited mRNAs in trypanosome mitochondrial extracts

Molecular and Cellular Biology 12(6): 2591-2598

RNA editing in T. brucei is a posttranscriptional processing event that results in the addition and deletion of uridine residues within several mitochondrial mRNAs. Reactions involving pre-edited precursor RNAs were examined in vitro. In this study, specific cleavage of pre-edited cytochrome b (CYb), cytochrome oxidase subunit II (COII), and cytochrome subunit III (COIII) mRNAs when incubated with T. brucei mitochondrial extracts is reported.

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Accession: 002226692

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PMID: 1375322

DOI: 10.1128/mcb.12.6.2591

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