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The 5'-flanking sequence of the loach oocyte 5S rRNA gene contains a signal for effective transcription


Gene 90(2): 243-248
The 5'-flanking sequence of the loach oocyte 5S rRNA gene contains a signal for effective transcription
Deletion mutants of loach oocyte 5S rRNA genes were transcribed after transfer into the nuclei of loach (Misgurnus fossilis) and Xenopus laevis. A control region was found in the 5'-flanking sequence, the deletion of which greatly decreased in vivo transcription of 5S rRNA genes. This cis-acting element was located in the region between nucleotide -18 and the transcription start point.


Accession: 002241216

PMID: 2401403

DOI: 10.1016/0378-1119(90)90186-U



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