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The electrophoretic difference between A and B variants of cattle beta -lactoglobulin corresponds to an HphI RFLP in exon III


, : The electrophoretic difference between A and B variants of cattle beta -lactoglobulin corresponds to an HphI RFLP in exon III. Animal Biotechnology 2(1): 31-43

As the HaeIII enzyme gives rise to larger diagnostic fragments, and is also currently 10-fold cheaper than the HphI enzyme, it would be preferable to use the HaeIII site as a marker for the A and B variants of beta -lactoglobulin (BLG). This would only be possible if there is strong linkage disequilibrium between the causative (HphI) and marker (HaeIII) sites, which are 1.178 kb apart.

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