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The epidemiology and pathogenesis of trachoma


, : The epidemiology and pathogenesis of trachoma. Reviews in Medical Microbiology 3(2): 112-119

Trachoma remains the leading infectious cause of blindness. It is believed to afflict some 500 million people worldwide, of whom 7 million are blind as a consequence. The causative agent, Chlamydia trachomatis (serotypes A-C), is spread from eye to eye under conditions of poor hygiene; repeated reinfection results in scarring of the conjunctiva which may lead to corneal trauma and hence blindness.

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Related references

Mkocha, H.; Munoz, B.; West, S., 2010: Trachoma and ocular Chlamydia trachomatis rates in children in trachoma-endemic communities enrolled for at least three years in the Tanzania National Trachoma Control Programme. Trachoma, a blinding eye disease caused by repeated and prolonged infection with Chlamydia trachomatis, is a significant public health problem for sub-Saharan Africa. Tanzania has had a National Trachoma Task Force since 1999, working on trachoma...

Maccallan, A.F., 1931: The Epidemiology Of Trachoma. British Journal of Ophthalmology 15(7): 369-411

Blagojević, M.; Debeljković, N., 1971: Epidemiology of trachoma. Narodno Zdravlje 27(8): 288-292

Jin, X.Y.; Zhang, X.L.; Zhang, W.H.; Wang, X.L.; Sun, X.L.; Zhao, W.; Luo, S.Y., 1980: Pathogenesis of trachoma. The pathogenesis of trachoma is discussed including the conjunctival cytology, follicular pathology and chlamydial toxin pathogenic action on human eyes. The toxin is the main factor in producing the acute symptoms. Proliferative inflammation runs...

D.Freitas, C.A., 1957: Epidemiology and control of trachoma. The spread of trachoma depends on overcrowding, substandard living conditions and migration. Control is based on mass treatment to reduce sources of infection, plus education and improvement of the environment. Campaigns in schools, military estab...

Das, T.; Nirankari, M.S.; Chaddah, M.R., 1961: Trachoma (epidemiology and treatment). Journal of the All-India Ophthalmological Society 9: 72-76

Torres, A.L., 1949: Trachoma, its epidemiology and prevention. Hospital 35(6): 805-817

Treharne, J.D., 1985: The community epidemiology of trachoma. Effective eradication of avoidable blindness due to trachoma requires an understanding of the epidemiologic determinants that promote the disease. These determinants include both host factors, such as age, sex, and race, and environmental determin...

Torres, A.L., 1952: Trachoma, its epidemiology and prophylaxis. Folha Medica 33(20): 161-165

Treharne, J.D., 1988: The microbial epidemiology of trachoma. Detailed longitudinal studies of the microbiology of endemic trachoma in field situations have provided useful information concerning the epidemiology of this blinding disease. This knowledge should be of particular value for the further developme...