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The rational design of fungal lanosterol C14 demethylase inhibitors

Marriott, M.S.

Molecular aspects of chemotherapy Proceedings of the Second International Symposium, Gdansk, Poland, July 5-8, 1988: 193-204

1990


Accession: 002257134

The rational design of medically important inhibitors of fungal lanosterol C14 demethylase such as azoles is discussed in terms of structure-activity relationships relevant to intrinsic potency and in vitro and in vivo activity.

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