+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

A silver-impregnation and immunocytochemical study of innervation of the distal sesamoid bone and its suspensory ligaments in the horse

A silver-impregnation and immunocytochemical study of innervation of the distal sesamoid bone and its suspensory ligaments in the horse

Equine Veterinary Journal 26(3): 212-219

The innervation of the navicular bone (os sesamoideum distale) and its suspensory ligaments (ligamenta sesamoidea collateralia) (CSL) or proximal suspensory ligament and the ligamentum sesamoideum distale impar or the distal sesamoidean impar ligament (DS-impar ligament) was examined using combined anatomical techniques of silver impregnation and immunocytochemistry. Silver impregnation studies revealed an abundance of nerve fibres present in both the CSL and DS-impar ligament with the latter having relatively more nerve fibres. These silver-impregnated nerves coursed parallel to and were associated with the vasculature rather than appearing to innervate the vessels. Immunocytochemistry identified several sensory-related neuropeptides (calcitonin gene-related peptide (CGRP), substance P (SP) and neurokinin A (NKA)) in the nerves of the navicular bone and suspensory ligaments. More peptidergic nerves were evident within the synovial membrane and loose connective tissue in the dorsal part than in the palmar aspect or the CSL. In the CSL along the synovial membrane bordering the distal interphalangeal joint, the CGRP, SP and NKA were present in the nerves of vessels as well as the intimal layer of the distal interphalangeal joint. In the DS-impar ligament, there were many more nerves innervating vessels and the synovial membrane between the navicular bone and the third phalanx than were present in these structures in the CSL. Nerves with all 3 peptides entered the navicular bone via the proximal border and the distal groove to innervate the perichondrium, trabeculae and osteons. SP-like nerves also innervated the cortical bone underlying the articular cartilage. We suggest that these sensory nerve peptides contribute to the pathology of the navicular syndrome. The distribution of the nerves in the CSL and the DS-impar ligament could explain the clinical effects of local anaesthetics injected into the distal interphalangeal joint.

(PDF emailed within 0-6 h: $19.90)

Accession: 002288649

Download citation: RISBibTeXText

PMID: 8542841

DOI: 10.1111/j.2042-3306.1994.tb04372.x

Related references

Experimental functional investigations on the distal part of the suspensory apparatus of the horse in regard to sesamoid dehiscence after rupture. 1990

Injection of platelet- and leukocyte-rich plasma at the junction of the proximal sesamoid bone and the suspensory ligament branch for treatment of yearling Thoroughbreds with proximal sesamoid bone inflammation and associated suspensory ligament branch desmitis. Journal of the American Veterinary Medical Association 243(1): 120-125, 2014

Anatomy of the distal interphalangeal joint of the mature horse: relationships with navicular suspensory ligaments, sensory nerves and neurovascular bundle. Equine Veterinary Journal 29(2): 126-135, 1997

Putative role of the collateral ligaments of the distal sesamoid bone in Equus. SICB Annual Meeting & Exhibition Final Program & Abstracts : 130, 2003

Sesamoid dehiscence after partial and total rupture of the distal sesamoid ligaments. Pferdeheilkunde 7(6): 335-340, 343-345, 1991

Congenital bony ankylosis of the distal interphalangeal joint and distal sesamoid bone dysplasia in a horse. Veterinary Record 146(25): 736-737, 2000

Aseptic necrosis of the palmar and plantar ligaments (of the distal sesamoid bone of horses). Die aseptische Nekrose im Ligamentum palmare beziehungsweise plantare: 106, 1985

Collateral ligaments of the distal sesamoid bone in the digit of Equus: re-evaluating midstance function. Journal of Morphology 267(10): 1177-1185, 2006

Differences in the morphology of distal border synovial invaginations of the distal sesamoid bone in the horse as evaluated by computed tomography compared with radiography. Equine Veterinary Journal 44(6): 679-683, 2013

Distal sesamoid bone fractures in the horse. 8 Arbeitstagung der Fachgruppe Pferdekrankheiten, 6-8 Oktober 1982 in Freiburg: 38-43, 1982

X-ray findings of the distal sesamoid bone of the horse. Dtw. Deutsche Tierarztliche Wochenschrift 87(9): 344-345, 1980

Comparison of radiographic findings in the distal sesamoid (navicular) bone of the Freiberger horse and the Swiss Warmblood: a retrospective study (1983-1991). Pratique Veterinaire Equine 30(117): 43-54, 1998

Surgical treatment of fractures of the distal sesamoid bone in the horse. Bulletin de l' Academie Veterinaire de France 70(4): 433-438, 1997

Histological study of the innervation of the suspensory ligament of the forelimb of the horse. Veterinary Record 142(22): 606-610, 1998

Computed tomographic morphology of the synovial invaginations of the distal sesamoid bone of the horse. Anatomia, Histologia, Embryologia 40(1): 55-60, 2011